THE INCIDENCE OF POSTOPERATIVE NAUSEA AND VOMITING IN THE CENTRAL SURGERY UNIT AT PROF. DR. I.G.N.G. NGOERAH GENERAL HOSPITAL
Abstract
Latar belakang :PONV merupakan kejadian mual muntah pasca operasi yang umum terjadi, dan merupakan kejadian yang tidak nyaman dan tidak menyenangkan kepada pasien karena dapat memperlama waktu rawat inap dan meningkatkan pengeluaran. Tujuan: Tujuan dari penelitian ini adalah untuk mencari tahu jumlah kejadian PONV di RSUP Prof dr. I.G.N.G Ngoerah dan distribusi atau karateristik kejadian PONV berdasarkan beberapa faktor sepert; jenis kelamin, usia, kebiasaan merokok, jenis operasi, jenis anestesi, durasi operasi, dan riwayat kemoterapi. Metode: Penelitian jenis observasional dengan pendekatan deskriptif metode cross sectional dengan jumlah sampel 84, dengan menerapkan analisis bivariat untuk melihat peluang persentase faktor independen PONV terhadap kejadian PONV. Hasil: Terdapat kejadian PONV sebanyak 26 pasien dari 84 pasien dengan persentase 31%, dengan distribusi kejadian PONV berdasarkan faktor independen dengan persentase yaitu; Perempuan(36%), Usia 46 – 65 tahun(35,6%), bukan perokok(36,2%), jenis operasi potensi PONV(37%), anestesi umum(35,2%), durasi operasi >2 jam (50%), dan riwayat kemoterapi(40%) Kesimpulan: Berdasarkan penelitian ini, predictor independent PONV yang paling banyak ditemui adalah durasi operasi >2 jam (p=0,002). Tidak cukup bukti mengenai sejumlah faktor riwayat kemoterapi terhadap terjadinya PONV.
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References
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15. East J, Mitchell D. Article in The West Indian medical journal. 2009 [cited 2022 May 26]; Available from: https://www.researchgate.net/publication/51594920
16. Tramèr MR. Strategies for postoperative nausea and vomiting. Best Pract Res Clin Anaesthesiol [Internet]. 2004 Dec [cited 2022 May 30];18(4):693–701. Available from: https://pubmed.ncbi.nlm.nih.gov/15460553/
17. Aapro M. Granisetron: an update on its clinical use in the management of nausea and vomiting. Oncologist [Internet]. 2004 Nov 1 [cited 2022 May 30];9(6):673–86. Available from: https://pubmed.ncbi.nlm.nih.gov/15561811/
18. Apfel CC, Stoecklein K, Lipfert P. PONV: a problem of inhalational anaesthesia? Best Pract Res Clin Anaesthesiol [Internet]. 2005 [cited 2022 May 30];19(3):485–500. Available from: https://pubmed.ncbi.nlm.nih.gov/16013696/
19. Collins AS. Postoperative nausea and vomiting in adults: implications for critical care. Crit Care Nurse [Internet]. 2011 Dec 1 [cited 2022 May 26];31(6):36–45. Available from: https://pubmed.ncbi.nlm.nih.gov/22135330/
20. Genç A, Can G, Aydiner A. The efficiency of the acupressure in prevention of the chemotherapy-induced nausea and vomiting. Support Care Cancer [Internet]. 2013 Jan [cited 2022 May 30];21(1):253–61. Available from: https://pubmed.ncbi.nlm.nih.gov/22678407/
21. Desen W. Buku ajar onkologi klinis [Internet]. Balai Penerbit Fakultas Kedokteran Universitas Indonesia . 2013 [cited 2022 May 30]. Available from: https://lib.ui.ac.id/detail?id=20417330&lokasi=lokal
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25. Hesketh PJ. Chemotherapy-induced nausea and vomiting. N Engl J Med [Internet]. 2008 Jun 5 [cited 2022 May 30];358(23):2482–94. Available from: https://pubmed.ncbi.nlm.nih.gov/18525044/
26. Janicki PK, Sugino S. Genetic factors associated with pharmacotherapy and background sensitivity to postoperative and chemotherapy-induced nausea and vomiting. Exp Brain Res [Internet]. 2014;232(8):2613–25. Available from: http://dx.doi.org/10.1007/s00221-014-3968-z
27. Smith HS SESB. Postoperative nausea and vomiting. Ann Palliat Med [Internet]. 2012 Oct 1 [cited 2022 May 31];1(2):625–9. Available from: https://pubmed.ncbi.nlm.nih.gov/25841469/
28. Watcha MF, White PF. Postoperative nausea and vomiting. Anesthesiology [Internet]. 1992;77(1):162–84. Available from: http://dx.doi.org/10.1097/00000542-199207000-00023
29. Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting. Anesthesiology [Internet]. 1999;91(3):693–693. Available from: http://dx.doi.org/10.1097/00000542-199909000-00022
30. Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, et al. Fourth consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg [Internet]. 2020;131(2):411–48. Available from: http://dx.doi.org/10.1213/ANE.0000000000004833
31. Eberhart LHJ, Morin AM, Guber D, Kretz FJ, Schäuffelen A, Treiber H, et al. Applicability of risk scores for postoperative nausea and vomiting in adults to paediatric patients. Br J Anaesth [Internet]. 2004;93(3):386–92. Available from: http://dx.doi.org/10.1093/bja/aeh221
32. Yatabe T, Tamura T, Yamashita K, Yokoyama M. Influence of dexmedetomidine on cognitive function in volunteers. J Clin Anesth [Internet]. 2016;33:92–6. Available from: http://dx.doi.org/10.1016/j.jclinane.2016.03.017
33. Janicki PK, Sugino S. Genetic factors associated with pharmacotherapy and background sensitivity to postoperative and chemotherapy-induced nausea and vomiting. Exp Brain Res [Internet]. 2014;232(8):2613–25. Available from: http://dx.doi.org/10.1007/s00221-014-3968-z
34. Apfel CC, Korttila K, Abdalla M, Kerger H, Turan A, Vedder I, et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med [Internet]. 2004;350(24):2441–51. Available from: http://dx.doi.org/10.1056/NEJMoa032196
35. Eberhart LHJ, Morin AM. Risk scores for predicting postoperative nausea and vomiting are clinically useful tools and should be used in every patient: con--’life is really simple, but we insist on making it complicated’. Eur J Anaesthesiol [Internet]. 2011;28(3):155–9. Available from: http://dx.doi.org/10.1097/EJA.0b013e3283427f4f
2. Shiraishi-Zapata CJ, Arellano-Adrianzén SJ, Rodríguez-Velarde GJ, Shiraishi-Zapata CJ, Arellano-Adrianzén SJ, Rodríguez-Velarde GJ. Cumulative incidence and risks factors for postoperative nausea and vomiting in adult patients undergoing cholecystectomy under balanced general anesthesia: a prospective cohort study. Colombian Journal of Anestesiology [Internet]. 2020 Jan 1 [cited 2022 Apr 2];48(1):3–11. Available from: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-33472020000100003&lng=en&nrm=iso&tlng=en
3. Chatterjee et all. Figure 1 | Current Concepts in the Management of Postoperative Nausea and Vomiting [Internet]. web page . 2011 [cited 2022 May 11]. Available from: https://www.hindawi.com/journals/arp/2011/748031/fig1/
4. Charles Vacanti SS, PS and RU. Managementof postoperative nausea and vomiting. Essential Clinical Anesthesia [Internet]. 2011 Jan 1 [cited 2022 May 11];326–9. Available from: https://www.cambridge.org/core/books/essential-clinical-anesthesia/managementof-postoperative-nausea-and-vomiting/1F6E73C1FA57F621975076E4ED9CE338
5. Chatterjee S, Rudra A, Sengupta S. Current concepts in the management of postoperative nausea and vomiting. Anesthesiol Res Pract [Internet]. 2011 [cited 2022 May 21];2011. Available from: https://pubmed.ncbi.nlm.nih.gov/22110499/
6. Jin Z, Gan TJ, Bergese SD. Prevention and Treatment of Postoperative Nausea and Vomiting (PONV): A Review of Current Recommendations and Emerging Therapies. Ther Clin Risk Manag [Internet]. 2020 Dec 31 [cited 2022 May 28];16:1305–17. Available from: https://www.dovepress.com/prevention-and-treatment-of-postoperative-nausea-and-vomiting-ponv-a-r-peer-reviewed-fulltext-article-TCRM
7. Windri TM, Kinasih A, Pratiwi T, Sanubari E, Universitas ), Wacana KS. Angkit Kinasih 2) , Thresia Pratiwi Elingsetyo Sanubari 3) 1444 JMP Online. Tabita Ma Windri. 2019;1(11):1444–51.
8. Doubravska © L, Dostalova K, Fritscherova S, Zapletalova J, Adamus M. INCIDENCE OF POSTOPERATIVE NAUSEA AND VOMITING IN PATIENTS AT A UNIVERSITY HOSPITAL. WHERE ARE WE TODAY? 2010;154(1):69–76.
9. Elsa Anggrahini. PERBEDAAN PEROKOK AKTIF DAN PEROKOK PASIF TERHADAP KEJADIAN POST OPERATIVE NAUSEA AND VOMITING PADA PASIEN GENERAL ANESTESI DI RSUD SLEMAN. 2017;7–8.
10. Whalen F, Sprung J, Burkle CM, Schroeder DR, Warner DO. Recent smoking behavior and postoperative nausea and vomiting. Anesth Analg [Internet]. 2006;103(1):70–5, table of contents. Available from: http://dx.doi.org/10.1213/01.ane.0000221435.14002.4c
11. Eberhart LHJ, Högel J, Seeling W, Staack AM, Geldner G, Georgieff M. Evaluation of three risk scores to predict postoperative nausea and vomiting. Acta Anaesthesiol Scand [Internet]. 2000 Apr 1 [cited 2022 May 26];44(4):480–8. Available from: https://onlinelibrary.wiley.com/doi/full/10.1034/j.1399-6576.2000.440422.x
12. Apfel CC, Apfel CC, Heidrich FM, Heidrich FM, Jukar-Rao S, Jukar-Rao S, et al. Evidence-based analysis of risk factors for postoperative nausea and vomiting. BJA: British Journal of Anaesthesia [Internet]. 2012; Available from: https://pubmed.ncbi.nlm.nih.gov/23035051
13. Chatterjee S, Chatterjee S, Chatterjee S, Rudra A, Rudra A, Sengupta S, et al. Current Concepts in the Management of Postoperative Nausea and Vomiting. Anesthesiol Res Pract [Internet]. 2011; Available from: https://pubmed.ncbi.nlm.nih.gov/22110499
14. Ahmed AB, Hobbs GJ, Curran JP. Randomized, placebo‐controlled trial of combination antiemetic prophylaxis for day‐case gynaecological laparoscopic surgery†. BJA: British Journal of Anaesthesia [Internet]. 2000 Oct 1 [cited 2022 May 26];85(5):678–82. Available from: https://academic.oup.com/bja/article/85/5/678/273903
15. East J, Mitchell D. Article in The West Indian medical journal. 2009 [cited 2022 May 26]; Available from: https://www.researchgate.net/publication/51594920
16. Tramèr MR. Strategies for postoperative nausea and vomiting. Best Pract Res Clin Anaesthesiol [Internet]. 2004 Dec [cited 2022 May 30];18(4):693–701. Available from: https://pubmed.ncbi.nlm.nih.gov/15460553/
17. Aapro M. Granisetron: an update on its clinical use in the management of nausea and vomiting. Oncologist [Internet]. 2004 Nov 1 [cited 2022 May 30];9(6):673–86. Available from: https://pubmed.ncbi.nlm.nih.gov/15561811/
18. Apfel CC, Stoecklein K, Lipfert P. PONV: a problem of inhalational anaesthesia? Best Pract Res Clin Anaesthesiol [Internet]. 2005 [cited 2022 May 30];19(3):485–500. Available from: https://pubmed.ncbi.nlm.nih.gov/16013696/
19. Collins AS. Postoperative nausea and vomiting in adults: implications for critical care. Crit Care Nurse [Internet]. 2011 Dec 1 [cited 2022 May 26];31(6):36–45. Available from: https://pubmed.ncbi.nlm.nih.gov/22135330/
20. Genç A, Can G, Aydiner A. The efficiency of the acupressure in prevention of the chemotherapy-induced nausea and vomiting. Support Care Cancer [Internet]. 2013 Jan [cited 2022 May 30];21(1):253–61. Available from: https://pubmed.ncbi.nlm.nih.gov/22678407/
21. Desen W. Buku ajar onkologi klinis [Internet]. Balai Penerbit Fakultas Kedokteran Universitas Indonesia . 2013 [cited 2022 May 30]. Available from: https://lib.ui.ac.id/detail?id=20417330&lokasi=lokal
22. National Cancer Institute. Cancer Drugs - NCI [Internet]. 2022 [cited 2022 May 30]. Available from: https://www.cancer.gov/about-cancer/treatment/drugs
23. Ignatavicius MLWDD. Medical-Surgical Nursing: Concepts for Interprofessional Collaborative Care [Internet]. Philadelphia: W.B. Saunders Company. 2017 [cited 2022 May 30]. Available from: https://bunker2.zlibcdn.com/dtoken/5f9bba84a33bb68aebad50a88ef4a421/Medical-Surgical%20Nursing%20Concepts%20for%20Interprofessional%20Collaborative%20Care%2C%20Single%20Volume%20%28%20etc.%29%20%28z-lib.org%29.pdf
24. Chan HK, Ismail S. Side effects of chemotherapy among cancer patients in a Malaysian General Hospital: experiences, perceptions and informational needs from clinical pharmacists. Asian Pac J Cancer Prev [Internet]. 2014 [cited 2022 May 30];15(13):5305–9. Available from: https://pubmed.ncbi.nlm.nih.gov/25040993/
25. Hesketh PJ. Chemotherapy-induced nausea and vomiting. N Engl J Med [Internet]. 2008 Jun 5 [cited 2022 May 30];358(23):2482–94. Available from: https://pubmed.ncbi.nlm.nih.gov/18525044/
26. Janicki PK, Sugino S. Genetic factors associated with pharmacotherapy and background sensitivity to postoperative and chemotherapy-induced nausea and vomiting. Exp Brain Res [Internet]. 2014;232(8):2613–25. Available from: http://dx.doi.org/10.1007/s00221-014-3968-z
27. Smith HS SESB. Postoperative nausea and vomiting. Ann Palliat Med [Internet]. 2012 Oct 1 [cited 2022 May 31];1(2):625–9. Available from: https://pubmed.ncbi.nlm.nih.gov/25841469/
28. Watcha MF, White PF. Postoperative nausea and vomiting. Anesthesiology [Internet]. 1992;77(1):162–84. Available from: http://dx.doi.org/10.1097/00000542-199207000-00023
29. Apfel CC, Läärä E, Koivuranta M, Greim CA, Roewer N. A simplified risk score for predicting postoperative nausea and vomiting. Anesthesiology [Internet]. 1999;91(3):693–693. Available from: http://dx.doi.org/10.1097/00000542-199909000-00022
30. Gan TJ, Belani KG, Bergese S, Chung F, Diemunsch P, Habib AS, et al. Fourth consensus guidelines for the management of postoperative nausea and vomiting. Anesth Analg [Internet]. 2020;131(2):411–48. Available from: http://dx.doi.org/10.1213/ANE.0000000000004833
31. Eberhart LHJ, Morin AM, Guber D, Kretz FJ, Schäuffelen A, Treiber H, et al. Applicability of risk scores for postoperative nausea and vomiting in adults to paediatric patients. Br J Anaesth [Internet]. 2004;93(3):386–92. Available from: http://dx.doi.org/10.1093/bja/aeh221
32. Yatabe T, Tamura T, Yamashita K, Yokoyama M. Influence of dexmedetomidine on cognitive function in volunteers. J Clin Anesth [Internet]. 2016;33:92–6. Available from: http://dx.doi.org/10.1016/j.jclinane.2016.03.017
33. Janicki PK, Sugino S. Genetic factors associated with pharmacotherapy and background sensitivity to postoperative and chemotherapy-induced nausea and vomiting. Exp Brain Res [Internet]. 2014;232(8):2613–25. Available from: http://dx.doi.org/10.1007/s00221-014-3968-z
34. Apfel CC, Korttila K, Abdalla M, Kerger H, Turan A, Vedder I, et al. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med [Internet]. 2004;350(24):2441–51. Available from: http://dx.doi.org/10.1056/NEJMoa032196
35. Eberhart LHJ, Morin AM. Risk scores for predicting postoperative nausea and vomiting are clinically useful tools and should be used in every patient: con--’life is really simple, but we insist on making it complicated’. Eur J Anaesthesiol [Internet]. 2011;28(3):155–9. Available from: http://dx.doi.org/10.1097/EJA.0b013e3283427f4f
Published
2025-04-06
How to Cite
BAGASKARA, Joshua Andito et al.
THE INCIDENCE OF POSTOPERATIVE NAUSEA AND VOMITING IN THE CENTRAL SURGERY UNIT AT PROF. DR. I.G.N.G. NGOERAH GENERAL HOSPITAL.
Essential: Essence of Scientific Medical Journal, [S.l.], v. 22, n. 2, p. 99-109, apr. 2025.
ISSN 2655-6472.
Available at: <https://ojs.unud.ac.id./index.php/essential/article/view/121990>. Date accessed: 20 apr. 2025.
doi: https://doi.org/10.24843/essential.v22i2.121990.
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